Experts projects reality on heart disease wrinkles

They were looking for the secrets of heart failure, for the misbehaviors inside the cells that lead to the flabby, inefficient thing that is a heart in congestive distress.

That's the beauty of basic science, Dr. Joseph Shapiro says. When the goal is simply to know, anything may be uncovered.

It has been his focus since he was a doctoral student in the lab of UT's Dr. Amir Askari, who has spent a career dissecting this cell portal's behavior.

Testing the medication on wrinkled skin will await the next round of development - so no volunteers, please. The researchers will have to develop animal models for wrinkles - something neither researchers' academic laboratories possesses.